Death Associated Protein 1 （DAP1） is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-gamma. The DAP1 protein is praline-rich and possesses one SH3 binding motif，as well as several consensus protein kinase phosphorylation sites. The protein is localized in the cytoplasma，however the detailed mechanism of its proapoptotic function is unclear.
應用類型
Western blotting （0.5-4 ug/ml） in samples from human， mouse and rat origins. However， the optimal conditions should be determined individually. The antibody detects the 25 kDa large subunit of caspase-8. It does not detect the full-length of caspase-8.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 96 of human DAP1.
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的DAP1蛋白發生免疫反應
保存建議
提供的100 ug DAP1抗體產品為無色溶液其濃度為0.2 mg/ml溶解于包含有50%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該DAP1抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
