TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog （Hh）-signaling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a combination of renal cysts and variable associated features which includes developmental anomalies of the central nervous system，hepatic ductal dysplasia and cysts，and polydactyly.
應用類型
Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3262BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 435 of rat TCTN2
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的TCTN2蛋白發生免疫反應
保存建議
提供的100 ug TCTN2抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該TCTN2抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
