Perforin （Pore-forming protein） is originally cloned from mouse cytotoxic T-lymphocyte （CTL）. It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes，and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infection.
應用類型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects both mouse and rat perforin. Cross activity to perforin of other species has not been determined.
免疫原
Recombinant rat perforin
來源宿主
兔
反應性
經檢測驗證，可與小鼠、大鼠種屬來源的Perforin蛋白發生免疫反應.
保存建議
提供的Perforin抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Perforin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
