ASC （also called TMS1） is a CARD domain containing protein. ASC induces apoptosis through activation of caspase-9 and inhibiting the survival of human breast cancer cells. Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The affinity purified antibody detects the 25 kDa human and rat ASC/TMS1. HL60 cell lysate can be used as a positive control.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 185 of human ASC
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的ASC/TMS1蛋白發生免疫反應.
保存建議
提供的ASC/TMS1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該ASC/TMS1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
