The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family，caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. 293 cell lysate can be used as a positive control. Detects the 43 kDa human caspase-4
免疫原
Synthetic peptide corresponding to the N-terminus of human Caspase-4
來源宿主
小鼠
反應性
經檢測驗證，可與人種屬來源的Caspase-4蛋白發生免疫反應.
保存建議
提供的Caspase-4抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有0.5% BSA， 1.5 mM 疊氮鈉和30%甘油.的PBS緩沖液中.請將該Caspase-4抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
