Bax is a Bcl-2 family pro-apoptotic protein. Bax promotes cell death by forming homodimers,which can be blocked by forming heterodimers with Bcl-2 or Bcl-XL. Bax has three different isoforms,which are Bax-,B,and g. The 21 kDa Bax- is the most common form in most of the cells and tissues.
應用類型
Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects the 21 kDa Bax in samples of human, mouse, and rat origins.
免疫原
Synthetic peptide surrounding amino acids 15 of human Bax.
來源宿主
小鼠
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的Bax蛋白發生免疫反應.
保存建議
提供的Bax抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Bax抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.