p53DINP1 （p53-dependent damage-inducible nuclear protein 1） encodes two proteins termed p53DINP1- （27 kDa） and p53DINP1-B （18 kDa）. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1 is expressed in many tissues and induced by a variety of stress agents including UV stress，mutagenic stress，heat shock，and oxidative stress.
應用類型
Western blotting （0.5-4 ug/ml） and Immunohistochemistry （5-10 ug/ml）. However， the optimal dilution conditions should be determined individually. Human Lung tissue lysate can be used as a positive control. The antibody detects the 27 kDa p53DINP1- in human， mouse， and rat samples. A lower band （~18 kDa） which represents the p53DINP1-B was also detected in certain tissue and cells.
免疫原
Synthetic peptide mapping to the N-terminus of human p53DINP1
來源宿主
兔
反應性
經檢測驗證，可與人小鼠、大鼠種屬來源的p53NIDP1蛋白發生免疫反應.
保存建議
提供的p53NIDP1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該p53NIDP1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
