FAF1 （Fas-associated protein factor 1） specifically interacts with the cytoplasmic domain of wild type，but not mutated，Fas in both yeast and mammalian cells. When transiently expressed in T cells，FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD，FADD，and RIP，FAF1 lacks a DDH （Death domain homologous region） and cannot induce apoptosis independent of Fas activation.
應用類型
Western blotting （0.5-4 ug/ml） and in immunoprecipitation and Immunohistochemistry. However， the optimal conditions should be determined individually. Rat kidney cell lysate can be used as a positive control.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 640 of human FAF1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的FAF1蛋白發生免疫反應.
保存建議
提供的FAF1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該FAF1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
