Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B,H,K,L,O,and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis,protein degradation,and apoptosis. Cathepsin K expression is highest in bone,cartilage,and skeletal muscle
應用類型
Western blotting (0.5-4 ug/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. Detects 43 kDa cathepsin K of human, mouse, and rat origin.
免疫原
Synthetic peptide surrounding amino acid 321 of rat cathepsin K
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的Cathepsin K 蛋白發生免疫反應.
保存建議
提供的Cathepsin K 抗體產品為100 ug 無色溶液,其濃度為0.2 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Cathepsin K 抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.