Elk-1 is a transcription factor that binds the serum response element （SRE） and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 （Ser383） is also a target of the stress-activated kinase SAPK/JNK.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody detects 62 kDa phosphorylated Elk-1 （Ser383） of human， mouse and rat origins.
免疫原
Synthetic peptide surrounding amino acid 383 of human Elk-1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Phospho-Elk-1蛋白發生免疫反應.
保存建議
提供的Phospho-Elk-1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02%硫柳汞的PBS緩沖液中.請將該Phospho-Elk-1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
