It has been proposed that high density lipoproteins （HDLs） function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions，it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） and mouse small intestine tissue Lysate （Cat.# 2601-100） can be used as positive controls. The antibody recognizes 70 kDa CETP of human & rat origins.
免疫原
Synthetic peptide corresponding to the C-terminus of human CETP
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、兔種屬來源的CETP蛋白 發生免疫反應.
保存建議
提供的CETP抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該CETP抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
