Chemokines play an important role in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups,CXCR and CCR,based on the 2 major classes of chemokines. CXCR5 is one of the CXCR receptors,which is expressed in a variety of cells.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 36 kDa CXCR5 of human origin. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 359 of human CXCR5
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的CXCR5蛋白發生免疫反應.
保存建議
提供的CXCR5抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該CXCR5抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.