Neurexins comprise a family of neuronal cell surface proteins present primarily in the brain. Neurexins are thought to serve as signaling receptors and may play a role in axon guidance and synaptogenesis. The cytoplasmic tail of neurexin interacts with the synaptic vesicle protein synaptotagmin and binds to CASK，a protein with homology to the PSD95 family of synaptic junction proteins.
應用類型
Western blotting （1:200-1000）. However， the optimal concentrations should be determined individually. The antibody recognizes both alpha （~170 kDa） and beta （~50 kDa） isoforms of Neurexin in samples from human， rat， and bovine origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 1112 of rat neurexin
來源宿主
兔
反應性
經檢測驗證，可與人、大鼠、牛種屬來源的Neurexin蛋白發生免疫反應.
保存建議
提供的Neurexin抗體產品為100 ul 無色溶液，其濃度為1.0mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Neurexin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
