SOD (Superoxide Dismutase) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically,SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide,and it also catalyzes prooxidant reactions,which include the peroxidase activity and hydroxyl radical generating activity. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases.
應用類型
Western blotting (0.5-4 ug/ml), immunoprecipitation (20 ug/ml) and Immunohistochemistry (20 ug/ml, frozen & paraffin). However, the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 131 of human SOD
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的SOD-1蛋白 發生免疫反應.
保存建議
提供的SOD-1抗體 產品為100 ug 無色溶液,其濃度為0.2 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該SOD-1抗體 產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.