Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli,including serum,hormones,and osmotic shock,etc. SGK has been involved in modulating anti-apoptotic and cell cycle regulation,as well as in activating certain potassium,sodium and chloride channels.
應用類型
Western blotting (0.5-4 ug/ml), immunoprecipitation (10-20 ug/ml). However, the optimal conditions should be determined individually. The antibody detects SGK from samples of human, mouse, and rat origins.
免疫原
Synthetic peptide corresponding to the C-terminus of human SGK
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的SGK蛋白發生免疫反應.
保存建議
提供的SGK抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該SGK抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.