Human HtrA2 （also designated Omi） is a novel member of the HtrA serine protease family and is highly homologous to HtrA （also known as L56 and HtrA1）. HtrA2 is ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides of 38 and 40 kDa and as an alternatively spliced form called D-Omi，which is predominately expressed in the kidney，colon and thyroid. Like HtrA，HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress，suggesting that it may possess a chaperone-like role under normal conditions.
應用類型
Western blotting （1-2 ug/ml） and immunofluorescence （20 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the full length and the mitochondria-processed HtrA2/Omi.
免疫原
Recombinant human HtrA2/Omi
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的HtrA2/Omi蛋白 發生免疫反應.
保存建議
提供的HtrA2/Omi抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02%硫柳汞的PBS緩沖液中.請將該HtrA2/Omi抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
