The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components,including collagen,gelatin,fibronectin,laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester,lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3,MMP-10,and MMP-11 activates procollagenase.
應用類型
Western blotting (1-4 ug/ml), immunoprecipitation (10-20 ug/ml), and Immunohistochemistry (15-25 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes MMP3 of human, mouse, and rat origins.
免疫原
Recombinant human MMP3
來源宿主
山羊
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的MMP-3蛋白 發生免疫反應.
保存建議
提供的MMP-3抗體 產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有50%甘油, 1% BSA和0.02% 疊氮鈉的PBS緩沖液中.請將該MMP-3抗體 產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.