Proteins of the matrix metalloprotease （MMP） family are involved in the breakdown of extracellular matrix in normal physiological processes，such as embryonic development，reproduction，and tissue remodeling as well as disease processes such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the MMP-3 of human， mouse， rat， horse， and rabbit origins. Reactivity to other species has not been tested. The antibody detects the 55 kDa full length and the 21 kDa cleavage fragment of MMP-3.
免疫原
Synthetic peptide surrounding amino acid 465 of rat MMP-3
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、馬、兔種屬來源的MMP-3蛋白 發生免疫反應.
保存建議
提供的MMP-3抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該MMP-3抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
