The Toll-like receptor （TLR） family of proteins are characterized by a highly conserved Toll homology （TH） domain，which is essential for Toll-induced signal transduction. TLR9 has been suggested as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. TLR9 is highly expressed in the spleen.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~113 kDa of full length and the 65 kDa cleaved fragment in Jurkat cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 931 of mouse TLR9
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、豬種屬來源的TLR9蛋白發生免疫反應.
保存建議
提供的TLR9抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞nn的PBS （pH 7.2）緩沖液中.請將該TLR9抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
