TROY (also designated TAJ),a member of the TNFR superfamily,exists as several isoforms that vary in functions. Full length TROY contains a cytoplasmic tail,which recruits tumor necrosis factor receptor-associated factor (TRAF) 2. The interaction between TROY and TRAF2 promotes cell survival through the NFκB signaling pathway. One truncated version of TROY,designated TNFRSF19,contains a shortened cytoplasmic tail,which prevents TNFRSF19 from activating the NFκB signal transduction pathway.
應用類型
Western blotting (1-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mouse TROY. Reactivity to other species has not been tested.
免疫原
Synthetic peptide mapping to the C-terminus of mouse TROY
來源宿主
兔
反應性
經檢測驗證,可與小鼠種屬來源的TROY/TAJ蛋白 發生免疫反應.
保存建議
提供的TROY/TAJ抗體 產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該TROY/TAJ抗體 產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.