Wnt gene family members，including Wnt-1 through Wnt-10，play a key role in regulating cellular growth and differentiation. Wnt-1 functions as a key regulator of cellular adhesion. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-1，Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus induced mouse mammary carcinomas.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes 34 kDa Wnt-2 in human and mouse samples， and to a lesser extent in rat sample. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 45 of human Wnt-2
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Wnt-2蛋白 發生免疫反應.
保存建議
提供的Wnt-2抗體 產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Wnt-2抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
