Wnt gene family members，including Wnt-1 through Wnt-10，play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich，secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue.
應用類型
Western blotting （1-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） and mouse small intestine tissue lysate （Cat.# 2601-100） can be used as a positive controls. The antibody recognizes 39 kDa Wnt-4 of human， mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 10 of human Wnt-4
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Wnt-4蛋白 發生免疫反應.
保存建議
提供的Wnt-4抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Wnt-4抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
