PPAR （Peroxisome proliferator-activated receptor） is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPAR is preferentially expressed in liver，skeletal muscle，heart and kidney. PPAR is involved in regulation of lipid homeostasis. Its ligands include fatty acids，NSAIDs，prostaglandins，leukotriene B4，etc. PPAR transcriptionally regulates a variety of genes for enzymes and proteins involved in fatty acid metabolism and oxidation.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~52 kDa PPAR in human sample. A ~28 kDa cleavage fragment can also be detected in samples of human， mouse， and rat origins.
免疫原
Synthetic peptide surrounding amino acid 25 of human PPAR
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、綿羊、豬種屬來源的PPAR-alpha蛋白 發生免疫反應.
保存建議
提供的PPAR-alpha抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該PPAR-alpha抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
