HDAC family are divided into two classes,I and II. Class I of the HDAC family comprises four members,HDAC-1,2,3,and 8. Class II of the HDAC family comprises HDAC-4,5,6,and 7,the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1,2 and 3 were expressed in various tissues,but the others (HDAC-4,5,6,and 7) showed tissue-specific expression patterns. These results suggest that each member of the HDAC family exhibits a different,individual substrate specificity and function in vivo.
應用類型
Western blotting (0.5-4 ug/ml), However, the optimal concentrations should be determined individually. The antibody recognizes 39 kDa HDAC-11 of human, mouse, and rat origins
免疫原
Synthetic peptide surrounding amino acid 269 of human HDAC-11
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的HDAC11蛋白發生免疫反應.
保存建議
提供的HDAC11抗體產品為100 ug 無色溶液,其濃度為0.2 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該HDAC11抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.