FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes，cardiac and skeletal ryanodine receptors and the inositol 1，4，5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors，FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.
應用類型
Western blot （0.5-4 ug/ml）， immunoprecipitation （2-10 ug/ml） and Immunohistochemistry （2-10 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human， mouse， and rat origins.
免疫原
Synthetic peptide surrounding amino acid 10 of mouse FKBP12
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的FKBP12蛋白發生免疫反應.
保存建議
提供的FKBP12抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該FKBP12抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
