Decorin is a member of the small,leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage,decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin,thrombospondin,C1q,epidermal growth factor receptor (EGFR),and TGF-B. It is believed that decorin also plays a role in the cell cycle of chondrocytes.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects ~32 kDa Decorin in samples from human origin. Jurkat cell lysate can be used as a positive control. Cross-reactivity to mouse, rat, pig and rabbit is expected due to sequence homology.
免疫原
Synthetic peptide surrounding amino acid 130 of human Decorin
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠、兔、豬種屬來源的Decorin蛋白發生免疫反應.
保存建議
提供的Decorin抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有25%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Decorin抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.