Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins,which includes CTGF,Cyr61 homolog,Fisp2. Cyr61 functions as an angiogenic inducer,stimulating cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Elevated expression of Cyr61 is observed during vessel growth,wound healing and chondrocyte differentiation.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100) and mouse small intestine tissue lysate (Cat.# 2601-100) can be used as positive controls. The antibody detects the full length and cleaved form of Cyr61 protein from samples of human, mouse and rat origins. Cross-reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 166 of mouse Cyr61
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的Cyr61蛋白發生免疫反應.
保存建議
提供的Cyr61抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該Cyr61抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.