MST-1 （Mammalian STE20-like kinase 1） is a serine/threonine kinase that has been implicated to play a role in chromatin condensation. Its C-terminal contains nuclear export signals which are released upon caspase mediated cleavage. The N-terminus portion of MST-1 then translocates to the nucleus and will promote chromatin condensation. The full length of MST-1 is localized to the cytoplasm.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control. The antibody recognizes MST-1/Krs-2 at 50-60 kDa in samples from human， mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 13 of Human MST-1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的MST-1/Krs-2蛋白發生免疫反應.
保存建議
提供的MST-1/Krs-2抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有0.1% BSA， 30%甘油和0.01%硫柳汞的PBS緩沖液中.請將該MST-1/Krs-2抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
