Tumor Endothelial Markers （TEMs，TEM 1-9） are recently identified genes，whose expression is elevated in tumor-associated endothelium. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of collagen a3（VI），a protein also preferentially expressed in tumor endothelium. It is thought that TEM8 may play a role in tumor angiogenesis.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~80-85 kDa doublet of TME8 in samples from human， mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 484 of Mouse TEM8
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的TEM-8/ATR1蛋白發生免疫反應.
保存建議
提供的TEM-8/ATR1抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有0.5% BSA， 30%甘油和0.01%硫柳汞的PBS緩沖液中.請將該TEM-8/ATR1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
