Bcl-rambo shares the common structural characteristics with other members of the anti-apoptotic Bcl-2 family members,but differs from them at its C-terminus,where a 250 amino acid sequence proceeds the membrance anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that it membrane anchor C-terminus region is responsible for its apoptotic activity,not its Bcl-2 homology motifs.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~56 kDa band in samples from human, mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 421 of Mouse Bcl-rambo
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的Bcl-Rambo蛋白發生免疫反應.
保存建議
提供的Bcl-Rambo抗體產品為100 ug 無色溶液,其濃度為0.2 mg/ml,溶解于包含有0.1% BSA, 30%甘油和0.01%硫柳汞的PBS緩沖液中.請將該Bcl-Rambo抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.