Dvl1，Dvl2，and Dvl3 are mammalian homologs of Dsh （disheveled） proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins，Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.
應用類型
Western blotting （0.5-4 ug/ml）. The optimal concentrations should be determined individually. A ~80 kDa band and a smaller ~45 kDa cleavage fragment can be detected.
免疫原
Synthetic peptide surrounding amino acid 583 of mouse Dvl3
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Dvl3蛋白發生免疫反應.
保存建議
提供的Dvl3抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Dvl3抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
