The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes,including cytoskeletal recognization,MAPK signaling,apoptotic signaling,control of phagocytes,NADPH oxidase and growth factor-induced neurite outgrowth. Research indicates that phosphorylation of serine 139 of PAK3 which is located in the kinase inhibitory domain,affects the kinase activity.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested.
免疫原
Synthetic peptide surrounding amino acid 548 of human PAK3
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的PAK3蛋白發生免疫反應.
保存建議
提供的PAK3抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該PAK3抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.