Histone acetyltransferases （HATs） have been implicated in a number of cellular functions including gene regulation，DNA synthesis，and repair. Histone acetyltransferases and deacetylases are，respectively，the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders，including cancer.
應用類型
Western blotting （1-2 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes 50 kDa HAT-1 from samples of human， mouse and rat origins. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 445 of human HAT-1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的HAT-1 蛋白發生免疫反應.
保存建議
提供的HAT-1 抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該HAT-1 抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
