Sodium glucose co transporters （SGLTs） are located in the brush-border membrane，but transported out of the cell across the basolateral membranes by a facilitated sugar transporter （GLUT）. At least three members of SGLTs （SGLT 1-3） have been cloned and characterized. SGLTs transport a methyl-D-glucoside （a-MDG），a non-metabolized model substrate，in Na-dependent manner. SGLT-1 does not discriminate a-MDG，glucose，and galactose. SGLT2/3 do not transport D-galactose efficiently.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects 74 kDa SGLT-2 from human， mouse， and rat origins. Reactivity to other species has not been determined. A ~55 kDa and a ~45 kDa bands can also been detected， representing the SGLT-2 cleavage fragments.
免疫原
Synthetic peptide near the N-terminus of mouse SGLT-2
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的SGLT-2蛋白發生免疫反應.
保存建議
提供的SGLT-2抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該SGLT-2抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
