BIK is a member of Pro-apoptotic Bcl-2 family proteins. Although Bik lacks Bcl-2 homologus region,BH1 and BH2,BIK interacts with Bcl-2 and Bcl-xL. BIK has been shown to induce apoptosis by activating caspase-9.
應用類型
Western blotting (2-6 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100), mouse small intestine (Cat.# 2601-100) and rat kidney (Cat.# 2702-100) can be used as positive controls. The antibody detects a ~17 kDa BIK in samples from human, mouse, and rat origins. A ~15 kDa cleavage fragment can also be detected
免疫原
Synthetic peptide mapping to N-terminus of human BIK
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的BIK蛋白發生免疫反應.
保存建議
提供的BIK抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該BIK抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.