BIF-1 （Bax interacting factor-1） is a 365 amino acid protein that interacts with Bax protein and influences cell survival and death. BIF-1 contains a Src homology 3 （SH3） domain in the C-terminus. Overexpression of BIF-1 promotes Bax conformational change，caspase activation，and apoptotic cell death.
應用類型
Western blotting （2-6 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects 40 kDa BIF-1 in samples from human， mouse， and rat origins. Jurkat cell lysate and rat kidney tissue lysates can be used as positive controls.
免疫原
Synthetic peptide surrounding amino acid 351 of human BIF
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的BIF蛋白發生免疫反應.
保存建議
提供的BIF抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）緩沖液中.請將該BIF抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
