Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2，a protein involved in Alzheimer’s disease，to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function，is a substrate for caspase-3，acts as a calcium regulated transcriptional suppressor，and interacts with A-type potassium channels.
應用類型
Western blotting （2-6 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects ~30 kDa Calsenilin in samples from human， mouse， and rat origins. Jurkat cell lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 107 of human Calsenilin
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Calsenilin蛋白發生免疫反應.
保存建議
提供的Calsenilin抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.1% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Calsenilin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
