Histone acetyltransferases （HATs） have been implicated in a number of cellular functions including gene regulation，DNA synthesis，and repair. Histone acetyltransferases and deacetylases are respectively，the enzymes devoted to thr addition and removal of acetyl groups from lysine residues on the Histone N-terminal trails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders，including cancer.
應用類型
Western blotting （2-6 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control. The antibody recognizes 220 kDa human HAT-3. A 50 kDa unknown band can also be detected. Reactivity to other species has not been determined.
免疫原
Synthetic peptide containing amino acids near the C-terminus of the human HAT-3
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的HAT-3蛋白發生免疫反應.
保存建議
提供的HAT-3抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該HAT-3抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
