Vasodilator-stimulated phosphoprotein （VASP） belongs to the Ena/VASP family of adaptor proteins linking the cytoskeletal system to the signal transduction pathways. VASP functions in cytoskeletal organization，fibroblast migration，platelet activation and axon guidance. Three phosphorylation sites，Ser157，Ser239 and Thr278，have been identified. Evidence suggests that VASP phosphorylation reduces its association with actin and has a negative effect on actin polymerization.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been determined. The antibody recognizes ~46 kDa VASP from samples of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 371 of human VASP
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的VASP蛋白發生免疫反應.
保存建議
提供的VASP抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該VASP抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
