The cysteine proteases termed lysosomal cathepsins have long been thought to be primarily involved in end-stage protein breakdown within lysosomal compartments. Cathepsin L functions to regulate cell cycle progression through proteolytic processing of the CDP/Cux transcription factor.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the mature form of Cathepsin L （25 kDa） from human， mouse and rat origins. Reactivity to other species has not been tested. Rat kidney tissue lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 223 of rat Cathepsin L
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Cathepsin L （Cleaved）蛋白發生免疫反應.
保存建議
提供的Cathepsin L （Cleaved）抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 1% BSA和0.02%硫柳汞的PBS緩沖液中.請將該Cathepsin L （Cleaved）抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
