FOXL2 is a nuclear protein specially expressed in eyelids and in fetal and adult ovarian follicular cells. Defects in FOXL2 are cause of blepharophimosis,ptosis and epicanthus inversus syndrome (BPES). It is an autosomal dominant disorder characterized by eyelid dysplasia,small palpebral fissures,drooping eyelids and a skin fold. It is also associated with female infertility.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the FOXL2 of human, mouse, and rat origins. Rat kidney tissue lysate (Cat.# 2702-100) can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 367of human FOXL2
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的FoxL2蛋白發生免疫反應.
保存建議
提供的FoxL2抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該FoxL2抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.