PPAR （Peroxisome proliferator-activated receptor） is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARg is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism，PPARg also modulates insulin sensitivity，cell proliferation and inflammation. The inhibition of PPARg transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARg.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa band， corresponding to PPARg （isoform CRA-c） in samples from human and mouse origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 262 of human PPARg isoform CRA-c
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠種屬來源的PPAR gamma蛋白發生免疫反應.
保存建議
提供的PPAR gamma抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該PPAR gamma抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
