Triglycerides form an important energy store in many living organisms. Adipose tissue serves as the primary storage depot for triglycerides in mammals. Lipolytic enzymes mobilize triglycerides during periods of starvation to provide organisms with necessary energy. Hormone-sensitive lipase （HSL），the first identified lipolytic enzyme，hydrolyzes triglycerides in mammalian adipose tissues. Additional lipolytic enzymes，including adipose triglyceride lipase （ATGL），have also been discovered. The primary function of ATGL is to catalyze the hydrolysis of the first ester bond of lipid molecules. This enzyme may provide diglyceride substrates for HSL hydrolysis. ATGL is abundantly expressed in murine white and brown adipose tissue，and is highly substrate specific. ATGL was independently identified as desnutrin and the TG-hydrolace inducible phospholipase-A2-z.
應用類型
Western blotting （0.5-4 ug/ml） and immunoprecipitation. recognizes 54 kDa ATGL in samples from human， mouse and rat origins. However， the optimal concentrations should be determined individually.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 385 of human ATGL
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的ATGLAntibody發生免疫反應.
保存建議
提供的ATGLAntibody產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該ATGLAntibody產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
