Yes-associated protein (YAP) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain containing proteins such as Nck,Crk,Src,and Abl. YAP is a transcriptional coactivator. It interacts with 13-3-3 and suppresses apoptosis.
應用類型
Western blotting (0.5-4 ug/ml). Jurkat cell lysate can be used as a positive control. Other applications have not been tested.
免疫原
Synthetic peptide surrounding amino acid 279 of human YAP1
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的YAP1蛋白發生免疫反應.
保存建議
提供的YAP1抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該YAP1抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.