CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T （Th2-type） cells. In contrast to other chemokine receptors，the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover，activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.
應用類型
Western blotting （2-6 ug/ml）. However， the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 32 of human CCR4
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、狗種屬來源的CCR4蛋白發生免疫反應.
保存建議
提供的CCR4抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該CCR4抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
