MGMT Antibody,O-6-methylguanine-DNA methyltransferase,O-6-methylguanine-DNA-alkyltransferase,Methylguanine DNA methyltransferase,Methylated DNA protein cysteine methyltransferase
MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair protein that response to DNA damage by removing methly or alkyl groups from the O6 position of guanine. MGMT protects normal cells from cytotoxic effects and is important in drug resistance to alkylating agents.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 8 of rat MGMT
來源宿主
兔
反應性
經檢測驗證,可與小鼠、大鼠種屬來源的MGMT蛋白發生免疫反應.
保存建議
提供的MGMT抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該MGMT抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.