Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a matrix receptor which binds to Collagens，Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK （midkine），a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity，such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been determined.
免疫原
Synthetic peptide surrounding amino acid 427 of human Syndecan-3
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、雞種屬來源的Syndecan-3蛋白發生免疫反應.
保存建議
提供的Syndecan-3抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Syndecan-3抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
