Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140kDA. The glycoslated form of MPO has a molecular weight of 92kDa and when undergoes a final glycoslyation,MPO forms subunits of 60kDa and 12kDa. In recent studies,MPO was shown to be involved in the initiation and progression of cardiovascular disease.
應用類型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 60-100 kDa MPO from samples of human, mouse, and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 765 of human MPO
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠種屬來源的Myeloperoxidase (MPO)蛋白發生免疫反應.
保存建議
提供的Myeloperoxidase (MPO)抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Myeloperoxidase (MPO)抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.