Non-T cell Activation Linker （NTAL） is also known as linker for activation of B cells （LAB），is a transmembrane adaptor protein. NTAL is expressed in B cells，mast cells，monocytes and NK cells. When NTAL is tyrosine phosphorylated，it recruits signalling molecules such as Grb2，Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome，a rare genetic disorder.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects a 22 kDa rat NTAL/LAB. Other species have not been determined.
免疫原
Synthetic peptide surrounding amino acid 187 of rat NTAL
來源宿主
兔
反應性
經檢測驗證，可與大鼠種屬來源的NATL/LAB蛋白發生免疫反應.
保存建議
提供的NATL/LAB抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞nn的PBS （pH 7.2）緩沖液中.請將該NATL/LAB抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
