Trek-1 and Trek-2 belong to the tandem-pore K+ channel family that has two pore-forming domains and four transmembrane segments. Trek-1 is expressed throughout the central nervous system whereas Trek-2 is found mostly in the cerebellum，spleen and testis. Trek-1 is activated by arachidonic acid and polyunsaturated fatty acids.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~47 kDa Trek 1 of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 417 of mouse Trek-1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Trek1蛋白發生免疫反應.
保存建議
提供的Trek1抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞nn的PBS （pH 7.2）緩沖液中.請將該Trek1抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
